Is the Artificial Sweetener Acesulfame Potassium Safe?

亚磺胺酸钾，也称为aceSulfame k或Ace-k，是六个人造甜味剂之一，已被批准在美国使用，如此美国食品和药物管理局（FDA）。其他五个是sucralose那saccharin, aspartame, neotame and advantame.

该main benefit of so-called nonnutritive sweeteners — which don't provide any vitamins, minerals or any other nutritional benefits — is that they "provide little, if any, calories,"Nancy Farrell Allen，RDN，为营养和营养学院发言人告诉Livestrong.com。

ACE-K特别是，她补充说，“具有良好的保质期，并在食品制备方法中稳定。”这意味着它不会随着时间的推移而失去味道，即使在加热时也保持甜度（这意味着它可以用于烘焙食品）。

由FDA批准的所有六个人造甜味剂被认为是“高强度”甜味剂，因为它们比常规糖（蔗糖）更甜。ACE-K比糖更甜的是200倍，说FDA.。

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FDA首次批准了1988年的乙酰磺胺钾，用于口香糖，饮料（包括速溶咖啡和茶），明胶和布丁。根据每个数据包的情况，它也被批准为糖替代品，根据每包不超过两茶匙糖，据original FDA approval。At the time, the FDA did not approve Ace-K for confections or hard or soft candy.

2003年，FDA.expanded its approvalof Ace-K so it could be used as a "general-purpose sweetener and flavor enhancer in food, not including meat and poultry." The compound is now found in a wide variety of foods and beverages including all the original food categories plus baked goods, frozen desserts,protein shakes和饮食饮料，说Farrell Allen。它也发现了一些柔软和硬的糖果和其他糖果。

Farrell Allen表示，ACE-K与其他甜味剂相结合时，它可以与其他甜味剂结合起来，因为它可以留下轻微的苦味。

您可以在Sunett和Sweet One的品牌名称下寻找ACE-K。它列在美国食品的成分面板上。作为AceSulfame K，Acesfulame Potassium或Ace-K，表示FDA，或有时在欧洲的E950。

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In 1980, the FDA banned the artificial sweetener cyclamate because of a concern that it might cause bladder cancer in laboratory animals, according to theNational Cancer Institute。随后的研究没有找到相同的风险，但仍然禁止仙客脂，而其他人造甜味剂则提出了同样的担忧。

So far, Ace-K and the other five approved sweeteners do not show any evidence of causing cancer. "Despite controversy in test results, the FDA and the European Union maintain that Ace-K is safe for consumer use," says Farrell Allen. "FDA listed it as a Grade I suggesting 'good/strong evidence supporting' its safety."

该FDA.'s approval of Ace-K was based on an analysis of several studies, most of them on animals, looking at the compound's effect on reproduction, metabolism, genetics and cancer, among other things. They showed no harm and also indicated that Ace-K isn't metabolized by the body. In other words, it is eliminated with other waste. However, note that Ace-K is not approved in meat or poultry because, the FDA says, there isn't enough data.

该National Cancer Society points out that the FDA didn't find any evidence that Ace-K caused cancer.

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不是每个人都同意ACE-K是安全的。该Center for Science in the Public Interest（CSPI）是一个消费者看门狗组，将ACE-K放在避免的物质列表中，说现有的研究日期并具有重要的缺陷。CSPI要求FDA进行更多的研究。

最近，研究人员，包括2017年期刊的作者普罗斯一体，提出了人造甜味剂一般的担忧可以实际上有助于肥胖和葡萄糖代谢。该普罗斯一体研究发现changes in the gut microbiome给予aceSulfame钾的小鼠。他们还报道了该化合物与雄性小鼠的体重增加有关，虽然不是雌性小鼠。

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1988年，FDA确定了乙酰磺胺钾的可接受的每日摄入量（ADI）为每千克（2.2磅）的体重每天为15毫克。根据FDA，如果每天在一生中消耗，这笔款是安全的。2003年裁决没有改变ACE-K的ADI。

这是一个130磅重的人的ADI达到了大约900毫克的ACE-K，这将依照International Food Information Council Foundation。

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